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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP4K3
All Species:
23.03
Human Site:
S853
Identified Species:
46.06
UniProt:
Q8IVH8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IVH8
NP_003609.2
894
101316
S853
N
E
V
T
Q
E
I
S
D
S
T
R
I
F
R
Chimpanzee
Pan troglodytes
XP_515427
1190
131887
S1149
N
E
V
T
Q
E
I
S
D
S
T
R
I
F
R
Rhesus Macaque
Macaca mulatta
A4K2T0
487
55587
R447
T
V
E
D
L
Q
K
R
L
L
A
L
D
P
M
Dog
Lupus familis
XP_532943
894
101330
S853
N
E
V
T
Q
E
I
S
D
N
T
R
I
F
R
Cat
Felis silvestris
Mouse
Mus musculus
Q99JP0
894
101159
S853
N
E
V
T
Q
E
I
S
D
N
T
R
I
F
R
Rat
Rattus norvegicus
Q924I2
873
98660
S832
N
E
V
T
Q
E
I
S
D
N
T
R
I
F
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509828
659
74637
M619
L
F
D
Y
A
R
Q
M
Q
R
L
P
V
A
I
Chicken
Gallus gallus
Q5ZJK4
486
55318
R446
S
V
D
E
L
Q
R
R
L
S
A
L
D
P
M
Frog
Xenopus laevis
Q6IP06
493
56486
R453
S
F
E
E
L
Q
M
R
L
K
A
L
D
P
M
Zebra Danio
Brachydanio rerio
Q7ZUQ3
492
56062
R452
D
F
E
E
L
Q
M
R
L
T
A
L
D
P
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396779
961
108519
S916
G
E
V
T
Q
E
I
S
D
P
S
R
T
Y
R
Nematode Worm
Caenorhab. elegans
Q23356
1096
122486
S925
F
K
S
F
G
S
L
S
H
V
P
L
I
V
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74
25.2
97.9
N.A.
95.9
94.1
N.A.
68
25.9
24.5
24.6
N.A.
N.A.
51.8
24
N.A.
Protein Similarity:
100
74.2
38.9
98.9
N.A.
97.6
95.7
N.A.
69.6
38.9
38.3
38.4
N.A.
N.A.
67.8
42.7
N.A.
P-Site Identity:
100
100
0
93.3
N.A.
93.3
93.3
N.A.
0
6.6
0
0
N.A.
N.A.
66.6
13.3
N.A.
P-Site Similarity:
100
100
6.6
100
N.A.
100
100
N.A.
6.6
20
20
26.6
N.A.
N.A.
80
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
0
0
0
34
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
17
9
0
0
0
0
50
0
0
0
34
0
9
% D
% Glu:
0
50
25
25
0
50
0
0
0
0
0
0
0
0
0
% E
% Phe:
9
25
0
9
0
0
0
0
0
0
0
0
0
42
0
% F
% Gly:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
50
0
0
0
0
0
50
0
9
% I
% Lys:
0
9
0
0
0
0
9
0
0
9
0
0
0
0
0
% K
% Leu:
9
0
0
0
34
0
9
0
34
9
9
42
0
0
0
% L
% Met:
0
0
0
0
0
0
17
9
0
0
0
0
0
0
34
% M
% Asn:
42
0
0
0
0
0
0
0
0
25
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
9
9
9
0
34
0
% P
% Gln:
0
0
0
0
50
34
9
0
9
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
9
9
34
0
9
0
50
0
0
50
% R
% Ser:
17
0
9
0
0
9
0
59
0
25
9
0
0
0
0
% S
% Thr:
9
0
0
50
0
0
0
0
0
9
42
0
9
0
0
% T
% Val:
0
17
50
0
0
0
0
0
0
9
0
0
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _